Wikipedia

5-MeO-MALT

5-MeO-MALT
Clinical data
Other names5-Methoxy-N-methyl-N-allyltryptamine
Drug classNon-selective serotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
Identifiers
  • N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H20N2O
Molar mass244.338 g·mol−1
3D model (JSmol)
  • COC2=CC=C1[NH]C=C(C1=C2)CCN(CC=C)C
  • InChI=1S/C15H20N2O/c1-4-8-17(2)9-7-12-11-16-15-6-5-13(18-3)10-14(12)15/h4-6,10-11,16H,1,7-9H2,2-3H3
  • Key:AJHGTCBMUIJSQL-UHFFFAOYSA-N

5-MeO-MALT, also known as 5-methoxy-N-methyl-N-allyltryptamine, is a psychedelic drug of the tryptamine family related to 5-MeO-DALT.[1][2][3]

5-MeO-MALT was first described in the literature in 2004.[1] It was encountered as a novel designer drug in 2014.[4][5] The drug's pharmacology was studied and described in greater detail in 2024.[6]

Interactions

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See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

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Pharmacodynamics

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The pharmacology of 5-MeO-MALT has been studied.[6] It is a potent serotonin 5-HT2A receptor agonist and produces the head-twitch response in rodents.[6] The drug also shows high affinity for the serotonin 5-HT1A receptor.[6]

Society and culture

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Hungary

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5-MeO-MALT is illegal in Hungary.[7]

Sweden

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Sweden's public health agency suggested classifying 5-MeO-MALT as a hazardous substance, on May 15, 2019.[8]

See also

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References

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  1. ^ a b Jensen N (4 November 2004). Tryptamines as Ligands and Modulators of the Serotonin 5-HT2A Receptor and the Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens (PDF) (Ph.D. thesis). Georg-August-Universität zu Göttingen. Retrieved 19 October 2015.
  2. ^ "5-MeO-MALT". WEDINOS - Welsh Emerging Drugs & Identification of Novel Substance Project. Public Health Wales. Retrieved 19 October 2015.
  3. ^ Holm-Nilsen S (30 April 2015). "Psykotisk ungdom ruset på motedop raserte pasientrom" [Psychotic adolescents intoxicated at fashion baptism demolished patient rooms] (in Norwegian). VG. Retrieved 19 October 2015.
  4. ^ EMCDDA (European Monitoring Centre for Drugs and Drug Addiction) (2015) New psychoactive substances in Europe - an update from the EU Early Warning System. Publications Office of the European Union, Luxembourg. http://www.emcdda.europa.eu/publications/ 2015/new-psychoactive-substances. Accessed 15 Nov 2015
  5. ^ Schifano F, Orsolini L, Papanti D, Corkery J (2017). "NPS: Medical Consequences Associated with Their Intake". Curr Top Behav Neurosci. 32: 351–380. doi:10.1007/7854_2016_15. PMID 27272067.
  6. ^ a b c d Puigseslloses P, Nadal-Gratacós N, Ketsela G, Weiss N, Berzosa X, Estrada-Tejedor R, Islam MN, Holy M, Niello M, Pubill D, Camarasa J, Escubedo E, Sitte HH, López-Arnau R (August 2024). "Structure-activity relationships of serotonergic 5-MeO-DMT derivatives: insights into psychoactive and thermoregulatory properties". Mol Psychiatry. 29 (8): 2346–2358. doi:10.1038/s41380-024-02506-8. PMC 11412900. PMID 38486047.
  7. ^ "A Magyarországon megjelent, a Kábítószer és Kábítószer-függőség Európai Megfigyelő Központjának Korai Jelzőrendszerébe (EMCDDA EWS)" [Early Warning System of the European Monitoring Center for Drugs and Drug Addiction, published in Hungary] (PDF). óta bejelentett ellenőrzött anyagok büntetőjogi vonatkozású besorolása [Criminal classification of controlled substances reported since 2005] (in Hungarian).
  8. ^ "Folkhälsomyndigheten föreslår att 20 ämnen klassas som narkotika eller hälsofarlig vara" [The Swedish Public Health Agency proposes that 20 substances be classified as drugs or dangerous goods] (in Swedish). Folkhälsomyndigheten. 15 May 2019. Archived from the original on 20 October 2021. Retrieved 11 November 2019.
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