6-MAPDB

6-MAPDB
Clinical data
Other names	6-(2-(Methylamino)propyl)-2,3-dihydrobenzofuran; 1-(2,3-Dihydrobenzofuran-6-yl)-N-methylpropan-2-amine
Legal status
Legal status	CA: Schedule I; DE: NpSG (Industrial and scientific use only); UK: Class B;
Identifiers
	IUPAC name 1-(2,3-dihydro-1-benzofuran-6-yl)-N-methylpropan-2-amine;
CAS Number	1354631-81-4;
PubChem CID	112500534;
ChemSpider	32078889;
UNII	1C25E596YG;
CompTox Dashboard (EPA)	DTXSID301045393 ;
Chemical and physical data
Formula	C12H17NO
Molar mass	191.274 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(CC1=CC2=C(CCO2)C=C1)NC;
	InChI InChI=1S/C12H17NO/c1-9(13-2)7-10-3-4-11-5-6-14-12(11)8-10/h3-4,8-9,13H,5-7H2,1-2H3; Key:ZKMVEORLSJXOBD-UHFFFAOYSA-N;

6-MAPDB, also known as 6-(2-(methylamino)propyl)-2,3-dihydrobenzofuran, is a chemical compound which may be an entactogen of the dihydrobenzofuran family. It is structurally related to drugs like 6-APDB and 6-MAPB, which have similar effects to MDMA and have been used as recreational drugs. 6-MAPDB has never been studied to determine its pharmacological activity, though it is the N-methyl derivative of 6-APDB which is known to be a selective serotonin releaser.^[1]

Interactions

Society and culture

Legal status

6-MAPDB was banned in the UK in June 2013 as a temporary class drug along with 9 other related compounds, despite having never been sold as a street drug itself. This was due to concerns that it would have similar effects to drugs such as 6-APB that had been widely sold already, and 6-MAPDB might therefore be likely to become used recreationally also, if it were not banned preemptively.^[2]

References

^ Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE (November 1993). "Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700–6. doi:10.1021/jm00075a027. PMID 8246240.
^ "Temporary class drug order on benzofury and NBOMe compounds - letter from ACMD". UK Home Office. 4 Jun 2013. Retrieved 2013-07-11.

External links

6-MAPDB - Isomer Design

[pmid8246240-1] Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE (November 1993). "Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine". Journal of Medicinal Chemistry. 36 (23): 3700–6. doi:10.1021/jm00075a027. PMID 8246240.

[ACMD_report-2] "Temporary class drug order on benzofury and NBOMe compounds - letter from ACMD". UK Home Office. 4 Jun 2013. Retrieved 2013-07-11.

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