
In medicine, atelectotrauma, atelectrauma, cyclic atelectasis or repeated alveolar collapse and expansion (RACE) is the damage caused to the lung by mechanical ventilation under certain conditions.
Disorder
[edit]When parts of the lung collapse at the end of expiration, due to a combination of a diseased lung state and a low functional residual capacity, then reopen again on inspiration, this repeated collapsing and reopening causes shear stress which has a damaging effect on the alveolus.[1][2] Clinicians attempt to reduce atelectotrauma by ensuring adequate positive end-expiratory pressure (PEEP) to maintain the alveoli open in expiration. This is known as open lung ventilation. High-frequency oscillatory ventilation (HFOV) with its use of super continuous positive airway pressure (CPAP) is especially effective in preventing atelectotrauma since it maintains a very high mean airway pressure (MAP), equivalent to a very high PEEP. Atelectotrauma is one of several means by which mechanical ventilation may damage the lungs leading to ventilator-associated lung injury. The other means are volutrauma, barotrauma, rheotrauma and biotrauma. Attempts have been made to combine these factors in an all encompassing term: mechanical power.
References
[edit]- ^ Shi, C.; Boehme, S.; Hartmann, E. K.; Markstaller, K. (Feb 2011). "Novel technologies to detect atelectotrauma in the injured lung". Exp Lung Res. 37 (1): 18–25. doi:10.3109/01902148.2010.501402. PMID 20860539.
- ^ Attar, MA; Donn, SM (Oct 2002). "Mechanisms of ventilator-induced lung injury in premature infants". Semin Neonatol. 7 (5): 353–60. PMID 12464497.