Wikipedia

2C-G-5

2C-G-5
Clinical data
Other names3,4-Norbornyl-2,5-DMPEA; 3,4-Norbornyl-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-3,4-norbornylphenethylamine; 3,6-Dimethoxy-4-(2-aminoethyl)benzonorbornane
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Onset of action1–2 hours[1]
Duration of action32–48 hours[1]
Identifiers
  • 2-(3,6-dimethoxy-4-tricyclo[6.2.1.02,7]undeca-2,4,6-trienyl)ethanamine
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H21NO2
Molar mass247.338 g·mol−1
3D model (JSmol)
  • COC1=C2C3CCC(C3)C2=C(C(=C1)CCN)OC
  • InChI=1S/C15H21NO2/c1-17-12-8-11(5-6-16)15(18-2)14-10-4-3-9(7-10)13(12)14/h8-10H,3-7,16H2,1-2H3
  • Key:ASPWVWSIJQTXDB-UHFFFAOYSA-N

2C-G-5, also known as 3,4-norbornyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.[1][2][3][4] It is one of several homologues of 2C-G (3,4-dimethyl-2,5-dimethoxyphenethylamine).[1][2][3][4] The drug is taken orally.[1][2][3]

Use and effects

[edit]

2C-G-5 has a dose of 10 to 16 mg orally, an onset of 1 to 2 hours, a peak of 2.5 to 3 hours, and a duration of 32 to 48 hours.[1][2][3] It produces psychedelic effects including visuals, clear and cosmic thinking, and 2C-B-like enhanced eroticism, among others.[1] 2C-G-5 is among the most potent of the 2C psychedelics.[1][2][3] However, its duration is described as too long, interfering with sleep and resulting in subsequent-day consequences like tiredness and sleepiness.[1]

Interactions

[edit]
See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Chemistry

[edit]

Synthesis

[edit]

The chemical synthesis of 2C-G-5 has been described.[1]

Analogues

[edit]

Analogues of 2C-G-5 include other compounds of the 2C-G and Ganesha series, among others.[1]

History

[edit]

2C-G-5 was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1][2][3][4]

See also

[edit]

References

[edit]
  1. ^ a b c d e f g h i j k l m Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. "2C-G-5".
  2. ^ a b c d e f Jacob P, Shulgin AT (1994). "Structure-activity relationships of the classic hallucinogens and their analogs" (PDF). NIDA Research Monograph. 146: 74–91. PMID 8742795. Archived from the original (PDF) on August 5, 2023.
  3. ^ a b c d e f Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Retrieved 1 February 2025.
  4. ^ a b c Shulgin A, Manning T, Daley P (2011). The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley: Transform Press. ISBN 978-0-9630096-3-0.
[edit]